PRF thermometry during MR-guided focused ultrasound ablation in a preclinical thiel model
نویسندگان
چکیده
Background/introduction Proton Resonance Frequency (PRF) MR Thermometry is a useful method for treatment planning with MR-guided Focused Ultrasound (MRgFUS), as it provides accurate, real-time temperature maps. Thiel is an embalming medium that retains physical properties and life-like characteristics of human and animal tissue. The aim of the present study was to determine the accuracy of PRF Thermometry during MRgFUS and to estimate the value of PRF coefficient of pre-clinical Thiel embalmed human and animal tissue, and compare to fresh tissue and gel phantom.
منابع مشابه
Improved k-space-based MR thermometry by joint PRF phase shift and T1/T2* attenuation estimation
Background/introduction MR temperature mapping based on the proton resonance frequency (PRF) shift is used in MR-guided focused ultrasound procedures for dosimetry and safety monitoring. While conventional PRF-shift thermometry is based on calculating a phase difference between two reconstructed MR images, Gaur et al [1,2] have recently described two algorithms that estimate temperatureinduced ...
متن کاملPET and MRI-guided focused ultrasound surgery for hypoxic-tissue ablation combined with radiotherapy in solid tumors
Background: The rationale was to develop an ablation approach to destroy regions of tumor resistant to radiation and thus reduce the time required for whole tumor ablation, while improving overall tumor control after radiotherapy. Materials and Methods: The system is composed of a micro positron emission tomography (mPET), 7T magnetic resonance imaging (MRI), and a customized MRI-compatible foc...
متن کاملThree dimensional motion compensation for real-time MRI guided focused ultrasound treatment of abdominal organs
Purpose/Introduction MR-guided High Intensity Focused Ultrasound (HIFU) for the ablation of tumors in abdominal organs under freebreathing conditions poses two challenges: 1) The current organ position in 3D-space must be continuously tracked in order to reposition the focal point of the HIFU-device to avoid undesired tissue damage. 2) Phase variations due to the organ displacement must be corr...
متن کامل3D MR neurography targeted peripheral nerve ablation with MR-guided high intensity focused ultrasound (MR-HIFU): initial results of a feasibility study in a swine model
Background/introduction MR-guided HIFU is an effective treatment for metastatic bone pain through periosteal nerve ablation,[1] and is being investigated for treating back pain through facet joint denervation.[2] For peripheral neuropathy, ultrasound-guided HIFU has been investigated preclinically as a means of achieving either an irreversible conduction block to treat severe spasticity [3], or...
متن کاملSonalleve MR-HIFU with DISC Philips MR-guided High Intensity Focused Ultrasound with Direct Skin Cooling
High Intensity Focused Ultrasound guided by Magnetic Resonance Imaging (also known as MR-guided HIFU, MRgHIFU, or MRgFUS) is a therapy technique which uses focused ultrasound waves to heat and coagulate tissue deep inside the body without damaging intervening tissue and offers an novel, non-invasive treatment option for solid tumors. The Philips Sonalleve MR-HIFU system, initially released in 2...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2014